Dynamic wrinkles and folds appear in areas of the face that move repetitively. Your face is dynamic, making millions of movements and micro-movements every day. Movements like squinting, frowning, laughing, and talking create dynamic wrinkles and folds. These wrinkles and folds can be difficult to treat because dermal fillers may cause the area to appear stiff or unnatural when the face moves.
RHA® Collection is designed to be resilient enough to adapt to your facial movement, which may provide a more natural look at rest and in motion.
What is RHA® 3?
RHA® 4 is an injectable gel (also called a dermal filler) used to treat facial wrinkles and folds. It is injected in the moving (dynamic) area of the face especially between the nose and corners of the mouth (nasolabial folds) (see Figure 1). It is approved for use in adults over 22 years of age.
RHA® 4 is produced with hyaluronic acid (HA), using an advanced technology to obtain a soft and long lasting injectable gel to smooth facial wrinkles and folds. The HA of the gel is made from a non-animal source.
RHA® 4 contains a small amount of an anesthetic medicine (lidocaine), to help reduce discomfort during injection Hyaluronic acid (HA) is a naturally occurring substance found in the human body. Your body’s own HA helps maintain the skin’s structure and its natural feel.
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| FAQs | What is RHA® Collection? The RHA® Collection is the first and only FDA-approved hyaluronic acid fillers for dynamic wrinkles and folds and includes three approved formulas: RHA® 2, RHA® 3, and RHA® 4. How is the RHA® Collection different than other dermal fillers? When can I expect to see results? |
| Treatment Type | Filler, Injectables |
| Treatment Problem or Condition | Facial Volume Loss, Wrinkles |
| Size | 1 cc syringe |
| Brand | Revance |
RHA® 4 is injected into the skin with an ultrafine needle to plump the skin to fill in and smooth away wrinkles and folds such as the lines from your nose to the corners of your mouth. This smoothing effect has been shown to last 12 months in 87% of the patients (67 out of 77 patients) and lasted 15 months in 89% of the patients (58 out of 65 patients).
RHA® 4 is not a permanent gel. It slowly goes away as the body absorbs the gel. The smoothing and plumping effect will gradually disappear.
The RHA® Collection is made with a gentle manufacturing process. This gentle process helps preserve the natural structure of the hyaluronic acid, allowing it to more closely resemble the natural hyaluronic acid in your skin.



